Article
Wild-type levels of the mouse Forkhead Box f1 gene are essential for lung repair.
American journal of physiology. Lung cellular and molecular physiology - 1 Jun 2002
Kalinichenko Vladimir V, Zhou Yan, Shin Brian, Stolz Donna Beer, Watkins Simon C, Whitsett Jeffrey A, Costa Robert H
Abstract excerpt
The Forkhead Box (Fox) family of transcription factors plays important roles in regulating expression of genes involved in cellular proliferation and differentiation. In a previous study, we showed that newborn foxf1(+/-) mice with diminished Foxf1 levels exhibited abnormal formation of pulmonary alveoli and capillaries and died postnatally. Interestingly, surviving newborn foxf1(+/-) mice exhibited increased...
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