Article
The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.
The Journal of biological chemistry - 10 Jun 2005
Kim Il-Man, Ramakrishna Sneha, Gusarova Galina A, Yoder Helena M, Costa Robert H, Kalinichenko Vladimir V
Abstract excerpt
Transgenic and gene knock-out studies demonstrated that the mouse Forkhead Box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B, Trident, Win, or MPP2) is essential for hepatocyte entry into mitosis during liver development, regeneration, and liver cancer. Targeted deletion of Foxm1 gene in mice produces an embryonic lethal phenotype due to severe abnormalities in the development of liver and...
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