Transcription factors in mouse lung development and function.

doi:10.1152/ajplung.2001.280.5.L823

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Article

Transcription factors in mouse lung development and function.

American journal of physiology. Lung cellular and molecular physiology - 1 May 2001

Costa R H, Kalinichenko V V, Lim L

Abstract excerpt

Development of the mouse lung initiates on day 9.5 postcoitum from the laryngotracheal groove and involves mesenchymal-epithelial interactions, in particular, those between the splanchnic mesoderm and epithelial cells (derived from foregut endoderm) that induce cellular proliferation, migration, and differentiation, resulting in branching morphogenesis. This developmental process mediates formation of the...

Topics

Amino Acid Motifs
Animals
Cell Differentiation
Epithelial Cells
Gene Expression Regulation, Developmental
Lung
Mesoderm
Mice
Mice, Knockout
Mice, Transgenic
Morphogenesis
Phenotype
Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 11290504
DOI: 10.1152/ajplung.2001.280.5.L823

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