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Article

New polymorphisms of haematopoietic prostaglandin D synthase and human prostanoid DP receptor genes.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2002

Noguchi E, Shibasaki M, Kamioka M, Yokouchi Y, Yamakawa-Kobayashi K, Hamaguchi H, Matsui A, Arinami T

Abstract excerpt

BACKGROUND: Prostaglandin D2 (PGD2), a major cyclo-oxygenase metabolite of arachidonic acid in mast cells, induces bronchoconstriction in the human lung. It has been reported that mice lacking PGD receptor fail to develop the bronchial hyper-responsiveness upon ovalbumin challenge, suggesting that PGD2 functions as a mediator of allergic asthma. OBJECTIVE: To determine if there are any mutations associated with...

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Source

Identifiers

PMID: 12002745
DOI: 10.1046/j.0022-0477.2001.01261.x

Genes

PTGDR
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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