Article
The prostaglandin D2 receptor (PTGDR) gene in asthma and allergic diseases.
Allergologia et immunopathologia - 1 Jan 2000
García-Solaesa V, Sanz-Lozano C, Padrón-Morales J, Hernández-Hernández L, García-Sánchez A, Rivera-Reigada M L, Dávila-González I, Lorente-Toledano F, Isidoro-García M
Abstract excerpt
The prostaglandin D2 receptor (PTGDR) gene has been associated to asthma and related phenotypes by linking and association studies. Functional studies involving animal models and other expression studies based on in vitro cell models also point to a possible role of polymorphisms in the promoter region, in the differential binding of transcription factors, and thus in PTGDR expression, which appear to be...
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