Article
Novel SNPs in a candidate gene, CRTH2, for allergic diseases.
Genes and immunity - 1 Apr 2002
Hsu S-C, Chen L-C, Kuo M-L, Huang J-L, Huang S-K
Abstract excerpt
Sequencing analyses of genomic DNA samples from a Chinese population identified four single-nucleotide polymorphisms (SNPs) of the CRTH2 gene, encoding a chemoattractant receptor predominantly expressed on Th2 cells and a receptor for prostaglandin D2 (PGD2). Two coding-region SNPs with a T to G and a C to A substitutions, resulting in codon changes from Phe to Val and Pro to Thr, respectively. Two additional...
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