Article
No association of PTGDR -441C/T polymorphism with asthma in a North Indian population.
Disease markers - 1 Jan 2011
Birbian Niti, Singh Jagtar, Jindal Surinder Kumar, Joshi Amit, Batra Navneet
Abstract excerpt
BACKGROUND: Asthma is the most prevalent disease in India according to the national survey conducted by NFHS 2 in 1998-399. Prostaglandin D2 (PGD2) is a bronchoconstriction inducing metabolite of arachidonic acid in the mast cells, which is produced on exposure to allergens and acts as a ligand for the Prostaglandin D2 Receptor (PTGDR). Polymorphisms in the PTGDR gene have been suggested to be involved in the...
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