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Article

Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Okuno Yutaka, Iwasaki Hiromi, Huettner Claudia S, Radomska Hanna S, Gonzalez David A, Tenen Daniel G, Akashi Koichi

Abstract excerpt

Human CD34 (hCD34)-positive cells are used currently as a source for hematopoietic transplantation in humans. However, in steady-state murine hematopoiesis, hematopoietic stem cells (HSCs) with long-term reconstitution activity are found almost exclusively in the murine CD34 (mCD34)-negative to low fraction. To evaluate the possible differences in hCD34 and mCD34 gene expression in hematopoiesis, we made...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11983914
DOI: 10.1073/pnas.092027799
PMCID: PMC122934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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