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Human CD34+ hematopoietic stem cell hierarchy: how far are we with its delineation at the most primitive level?

5 Apr 2023

Abstract excerpt

The ability to isolate and characterize different hematopoietic stem cell (HSC) or progenitor cell populations opens avenues to understand how hematopoiesis is regulated during development, homeostasis, and regeneration as well as in age-related conditions such as clonal hematopoiesis and leukemogenesis. Significant progress has been made in the past few decades in determining the composition of the cell types...

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PMID: 37018661
DOI: 10.1182/blood.2022018071

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