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Article

Role of CD34 Antigen in Myeloid Differentiation of Human Hematopoietic Progenitor Cells

10 Jan 2008

Abstract excerpt

CD34 is a transmembrane protein that is strongly expressed on hematopoietic stem/progenitor cells (HSCs); despite its importance as a marker of HSCs, its function is still poorly understood, although a role in cell adhesion has been demonstrated. To characterize the function of CD34 antigen on human HSCs, we examined, by both inhibition and overexpression, the role of CD34 in the regulation of HSC lineage...

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Identifiers

PMID: 18192237
DOI: 10.1634/stemcells.2007-0597

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