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Article

Human hematopoietic stem cell maintenance and myeloid cell development in next-generation humanized mouse models

29 Jan 2019

Abstract excerpt

Key Points Next-generation humanized mice differentially support human HSPC maintenance and myelopoiesis. MISTRG mice support long-term human HSPC maintenance demonstrated by quaternary transplantation and development of human tissue macrophages.

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Identifiers

PMID: 30696625
DOI: 10.1182/bloodadvances.2018023887

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