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Article

Distinct expression of cyclooxygenase-1 and -2 in the human thymus.

European journal of immunology - 1 May 2002

Rocca Bianca, Maggiano Nicola, Habib Aida, Petrucci Giovanna, Gessi Marco, Fattorossi Andrea, Lauriola Libero, Landolfi Raffaele, Ranelletti Franco O

Abstract excerpt

Cyclooxygenase (COX)-1 and -2 catalyze the formation of prostaglandins (PG). Given the role of COX and PG during intrathymic T cell development in the mouse, we investigated the expression and localization of these isozymes in the human thymus. mRNA and proteins correspondent to COX-1 and -2 were observed from whole thymus extracts. By immunohistochemistry, COX-2 was selectively localized in the medulla and it...

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Identifiers

PMID: 11981837
DOI: 10.1002/1521-4141(200205)32:5<1482::AID-IMMU1482>3.0.CO;2-O

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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