Article
5' flanking variants of resistin are associated with obesity.
Diabetes - 1 May 2002
Engert James C, Vohl Marie-Claude, Williams Scott M, Lepage Pierre, Loredo-Osti J C, Faith Janet, Doré Carole, Renaud Yannick, Burtt Noël P, Villeneuve Amélie, Hirschhorn Joel N, Altshuler David, Groop Leif C, Després Jean-Pierre, Gaudet Daniel, Hudson Thomas J
Abstract excerpt
Diabetes and obesity have long been known to be related. The recently characterized adipocyte hormone resistin (also called FIZZ3/ADSF) has been implicated as a molecular link between impaired glucose tolerance (IGT) and obesity in mice. A search for sequence variants at the human resistin locus identified nine single-nucleotide polymorphisms (SNPs) but no coding variants. An investigation into the association of...
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