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Article

Single nucleotide polymorphisms of the resistin (RSTN) gene.

Journal of human genetics - 1 Jan 2001

Cao H, Hegele R A

Abstract excerpt

Type 2 diabetes mellitus is a complex phenotype that is frequently associated with central obesity and insulin resistance. Recently, a protein named resistin, encoded by RSTN (OMIM #605565), was identified in adipose tissue. Serum resistin was elevated in obese and diabetic mice, and administration of resistin to normal mice was found to interfere with glucose tolerance and insulin action. Because of these...

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Identifiers

PMID: 11558907
DOI: 10.1007/s100380170040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Single nucleotide polymorphisms of the resistin (RSTN) gene.PMID 11558907Read ↗

Human Resistin Gene: Molecular Scanning and Evaluation of Association with Insulin Sensitivity and Type 2 Diabetes in CaucasiansSemantic proximity Read ↗

Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes.Semantic proximity Read ↗

Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study.Semantic proximity Read ↗

Plasma resistin concentration determined by common variants in the resistin gene and associated with metabolic traits in an aged Japanese population.Semantic proximity Read ↗

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians.Semantic proximity Read ↗

Human Resistin Gene, Obesity, and Type 2 DiabetesSemantic proximity Read ↗

Genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population.Semantic proximity Read ↗

Plasma resistin is associated with single nucleotide polymorphisms of a possible resistin receptor, the decorin gene, in the general Japanese population.Semantic proximity Read ↗

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.Semantic proximity Read ↗

Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels.Semantic proximity Read ↗

Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.Semantic proximity Read ↗

Polymorphisms of the resistin gene and their association with obesity and resistin levels in Malaysian Malays.Semantic proximity Read ↗

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