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Article

Human Resistin Gene, Obesity, and Type 2 Diabetes

1 Mar 2002

Abstract excerpt

The hormone resistin has been suggested to link obesity to type 2 diabetes by modulating steps in the insulin-signaling pathway and inducing insulin resistance. Thus, the resistin gene represents a potential candidate for the etiology of insulin resistance and type 2 diabetes. In this study, we analyzed the coding sequence of the three exons of the resistin gene, together with its 5' regulatory region and 3'...

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Identifiers

PMID: 11872692
DOI: 10.2337/diabetes.51.3.860

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Resistin Gene, Obesity, and Type 2 DiabetesPMID 11872692Read ↗

Genetic variants at the resistin locus and risk of type 2 diabetes in Caucasians.Semantic proximity Read ↗

Human Resistin Gene: Molecular Scanning and Evaluation of Association with Insulin Sensitivity and Type 2 Diabetes in CaucasiansSemantic proximity Read ↗

Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.Semantic proximity Read ↗

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.Semantic proximity Read ↗

Systematic search for single nucleotide polymorphisms in the resistin gene: the absence of evidence for the association of three identified single nucleotide polymorphisms with Japanese type 2 diabetes.Semantic proximity Read ↗

Single nucleotide polymorphisms of the resistin (RSTN) gene.Semantic proximity Read ↗

Resistin gene 3'-untranslated region +62G-->A polymorphism is associated with hypertension but not diabetes mellitus type 2 in a German population.Semantic proximity Read ↗

Association of Resistin Gene 3′-Untranslated Region +62G→A Polymorphism with Type 2 Diabetes and Hypertension in a Chinese PopulationSemantic proximity Read ↗

An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance.Semantic proximity Read ↗

The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes.Semantic proximity Read ↗

Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals.Semantic proximity Read ↗

Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study.Semantic proximity Read ↗

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