Article
Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study.
Diabetes - 1 Mar 2009
Hivert Marie-France, Manning Alisa K, McAteer Jarred B, Dupuis Josée, Fox Caroline S, Cupples L Adrienne, Meigs James B, Florez Jose C
Abstract excerpt
OBJECTIVE: The RETN gene encodes the adipokine resistin. Associations of RETN with plasma resistin levels, type 2 diabetes, and related metabolic traits have been inconsistent. Using comprehensive linkage disequilibrium mapping, we genotyped tag single nucleotide polymorphisms (SNPs) in RETN and tested associations with plasma resistin levels, risk of diabetes, and glycemic traits. RESEARCH DESIGN AND METHODS: We...
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