Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.

doi:10.1007/s00125-004-1537-x

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Article

Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.

Diabetologia - 1 Oct 2004

Conneely K N, Silander K, Scott L J, Mohlke K L, Lazaridis K N, Valle T T, Tuomilehto J, Bergman R N, Watanabe R M, Buchanan T A, Collins F S, Boehnke M

Abstract excerpt

AIMS/HYPOTHESIS: Resistin is a peptide hormone produced by adipocytes that is present at high levels in sera of obese mice and may be involved in glucose homeostasis through regulation of insulin sensitivity. Several studies in humans have found associations between polymorphisms in the resistin gene and obesity, insulin sensitivity and blood pressure. An association between variation in the resistin gene and...

Topics

3' Untranslated Regions
Age of Onset
Aged
Algorithms
Cohort Studies
Diabetes Mellitus, Type 2
Female
Finland
Genetic Variation
Genotype
Hormones, Ectopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Insulin

Introns

Male

Middle Aged

Obesity

Phenotype

Source

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Identifiers

PMID: 15517149
DOI: 10.1007/s00125-004-1537-x
PMCID: PMC1249496

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Variation in the resistin gene is associated with obesity and insulin-related phenotypes in Finnish subjects.PMID 15517149Read ↗

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