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Article

Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.

Free radical biology & medicine - 1 May 2002

Nishimura Susumu

Abstract excerpt

8-Hydroxyguanine (7,8-dihydro-8-oxoguanine, abbreviated as 8-OH-G or 8-oxoG) is the site of a frequent mutagenic DNA lesion produced by oxidative damage. MutM of E. coli and OGG1 of Saccharomyces cervisiae are known to possess 8-OH-G glycosylase and apurinic (AP) site lyase activity. cDNA clones of four isoforms (types 1a, 1b, 1c, and 2) of human OGG1 homologs (hMMH) were isolated. In order to examine whether...

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Identifiers

PMID: 11978483
DOI: 10.1016/s0891-5849(02)00778-5

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Involvement of mammalian OGG1(MMH) in excision of the 8-hydroxyguanine residue in DNA.PMID 11978483Read ↗

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