Article
Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling.
Developmental biology - 15 Sept 2007
Van Raay Terence J, Coffey Robert J, Solnica-Krezel Lilianna
Abstract excerpt
Wnt signaling controls a wide range of developmental processes and its aberrant regulation can lead to disease. To better understand the regulation of this pathway, we identified zebrafish homologues of Naked Cuticle (Nkd), Nkd1 and Nkd2, which have previously been shown to inhibit canonical Wnt/beta-catenin signaling. Zebrafish nkd1 expression increases substantially after the mid-blastula transition in a...
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