Article

Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin

2019-11-15

Abstract excerpt

Animal development and homeostasis depend on precise temporal and spatial intercellular signaling. Components shared between signaling pathways, generally thought to decrease specificity, paradoxically can also provide a solution to pathway coordination. Here we show that the Bone Morphogenetic Protein (BMP) and Wnt signaling pathways share Apcdd1 as a common inhibitor and that Apcdd1 is a taxon-restricted gene wi...

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Literature Corpus work: 087b598c-e89d-5163-8d36-8705263cc699
DOI: 10.1101/843714

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