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Article

Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation.

Kidney international - 1 May 2002

Strutz Frank, Zeisberg Michael, Ziyadeh Fuad N, Yang Chang-Qing, Kalluri Raghu, Müller Gerhard A, Neilson Eric G

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transformation (EMT) plays an important role in embryonic development and tumorigenesis and has been described in organ remodeling during fibrogenesis. In the kidney, EMT can be induced efficiently in cultured proximal tubular epithelium by coincubation of transforming growth factor (TGF)-beta1 and epidermal growth factor (EGF). Recently, we also have observed overexpression of...

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Source

Identifiers

PMID: 11967021
DOI: 10.1046/j.1523-1755.2002.00333.x

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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