Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability.

doi:10.1093/hmg/ddh279

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Article

Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability.

Human molecular genetics - 1 Nov 2004

Huang Jing-Long, Gao Pei-Song, Mathias Rasika A, Yao Tsung-Chieh, Chen Li-Chen, Kuo Ming-Ling, Hsu Shih-Chang, Plunkett Beverly, Togias Alkis, Barnes Kathleen C, Stellato Cristiana, Beaty Terri H, Huang Shau-Ku

Abstract excerpt

The gene, CRTH2, encoding a receptor for prostaglandin D(2) (PGD(2)), is located within the peak linkage region for asthma on chromosome (Chr.) 11q reported in African American families. Family-based analysis of asthma and two common SNPs [G1544C and G1651A (rs545659)] in the 3'-untranslated regi...

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PMID: 15345705
DOI: 10.1093/hmg/ddh279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15345705-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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