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Article

Genetic variation in CRTh2 influences development of allergic phenotypes.

Allergy - 1 Oct 2009

Cameron L, Depner M, Kormann M, Klopp N, Illig T, Von Mutius E, Kabesch M

Abstract excerpt

BACKGROUND: Allergic disorders are characterized by an increase in the Th2 cytokines IL-4, IL-5 and IL-13, produced primarily by Th2 cells. These cells are marked by the expression of CRTh2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), a receptor for prostaglandin D(2). As genetic variation plays a significant role in the predisposition for allergic disorders, we investigated the...

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Identifiers

PMID: 19392992
DOI: 10.1111/j.1398-9995.2009.02053.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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