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Article

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.

The Journal of allergy and clinical immunology - 1 Apr 2014

Xue Luzheng, Salimi Maryam, Panse Isabel, Mjösberg Jenny M, McKenzie Andrew N J, Spits Hergen, Klenerman Paul, Ogg Graham

Abstract excerpt

BACKGROUND: Activation of the group 2 innate lymphoid cell (ILC2) population leads to production of the classical type 2 cytokines, thus promoting type 2 immunity. Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2), a receptor for prostaglandin D₂ (PGD₂), is expressed by human ILC2s. However, the function of CRTH2 in these cells is unclear. OBJECTIVES: We sought to determine the role of...

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Source

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Identifiers

PMID: 24388011
DOI: 10.1016/j.jaci.2013.10.056
PMCID: PMC3979107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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