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Article

Selective Expression of a Novel Surface Molecule by Human Th2 Cells In Vivo

1 Feb 1999

Abstract excerpt

The search for reliable marker molecules discriminating between human Th1 and Th2 cells identified a gene encoding a novel member of the G protein-coupled leukocyte chemoattractant receptor family, which is selectively expressed in Th2 but not Th1 lineage cells, thereby named CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells). Studies with anti-CRTH2 mAbs demonstrated that CRTH2 was...

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PMID: 9973380
DOI: 10.4049/jimmunol.162.3.1278

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