Article
Genetic variations in chemoattractant receptor expressed on Th2 cells (CRTH2) is associated with asthma susceptibility in Chinese children.
Molecular biology reports - 1 Jul 2009
Wang Jinhui, Xu Yongchen, Zhao Hong, Sui Hong, Liang Hongyan, Jiang Xiaofeng
Abstract excerpt
We investigated the allele and genotype frequencies of two common CRTH2 single nucleotide polymorphisms (SNPs) [G1544C and A1651G (rs 545659)] in the 3'-untranslated region and the relationship between these SNPs and serum IL-13 levels in Chinese children patients with asthma. For G1544C and A1651G SNPs, there were significant differences in allele and genotype frequencies between asthma patients and controls....
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