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Article

Hes6 regulates myogenic differentiation.

Development (Cambridge, England) - 1 May 2002

Cossins Judy, Vernon Ann E, Zhang Yun, Philpott Anna, Jones Philip H

Abstract excerpt

Hes6 is a basic helix-loop-helix transcription factor homologous to Drosophila Enhancer of Split (EoS) proteins. It is known to promote neural differentiation and to bind to Hes1, a related protein that is part of the Notch signalling pathway, affecting Hes1-regulated transcription. We show that Hes6 is expressed in the murine embryonic myotome and is induced on C2C12 myoblast differentiation in vitro. Hes6 binds...

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Identifiers

PMID: 11959828
DOI: 10.1242/dev.129.9.2195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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