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Article

Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins.

Molecular and cellular biology - 1 Feb 1997

Lenormand J L, Benayoun B, Guillier M, Vandromme M, Leibovitch M P, Leibovitch S A

Abstract excerpt

The activities of myogenic basic helix-loop-helix (bHLH) factors are regulated by a number of different positive and negative signals. Extensive information has been published about the molecular mechanisms that interfere with the process of myogenic differentiation, but little is known about the positive signals. We previously showed that overexpression of rat Mos in C2C12 myoblasts increased the expression of...

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Identifiers

PMID: 9001211
DOI: 10.1128/MCB.17.2.584
PMCID: PMC231783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins.PMID 9001211Read ↗

Evidence that E-box promoter elements and MyoD transcription factors play a role in the induction of cathepsin B gene expression during human myoblast differentiation.Semantic proximity Read ↗

Mutation of MyoD-Ser237 abolishes its up-regulation by c-Mos.Semantic proximity Read ↗

MyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells.Semantic proximity Read ↗

Pax7-FKHR transcriptional activity is enhanced by transcriptionally repressed MyoD.Semantic proximity Read ↗

A splice variant of the ITF-2 transcript encodes a transcription factor that inhibits MyoD activity.Semantic proximity Read ↗

Hes6 regulates myogenic differentiation.Semantic proximity Read ↗

MEF-2 function is modified by a novel co-repressor, MITR.Semantic proximity Read ↗

Casein kinase II increases the transcriptional activities of MRF4 and MyoD independently of their direct phosphorylation.Semantic proximity Read ↗

Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation.Semantic proximity Read ↗

Transcriptional regulation of selenoprotein W by MyoD during early skeletal muscle differentiation.Semantic proximity Read ↗

Determinants of myogenic specificity within MyoD are required for noncanonical E box binding.Semantic proximity Read ↗

The basic region of myogenin cooperates with two transcription activation domains to induce muscle-specific transcription.Semantic proximity Read ↗

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