Article
A comparison of phasing algorithms for trios and unrelated individuals.
American journal of human genetics - 1 Mar 2006
Marchini Jonathan, Cutler David, Patterson Nick, Stephens Matthew, Eskin Eleazar, Halperin Eran, Lin Shin, Qin Zhaohui S, Munro Heather M, Abecasis Goncalo R, Donnelly Peter
Abstract excerpt
Knowledge of haplotype phase is valuable for many analysis methods in the study of disease, population, and evolutionary genetics. Considerable research effort has been devoted to the development of statistical and computational methods that infer haplotype phase from genotype data. Although a substantial number of such methods have been developed, they have focused principally on inference from unrelated...
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