Article
Comparison of haplotype inference methods using genotypic data from unrelated individuals.
Human heredity - 1 Jan 2004
Xu Hongyan, Wu Xifeng, Spitz Margaret R, Shete Sanjay
Abstract excerpt
OBJECTIVE: Haplotypes are gaining popularity in studies of human genetics because they contain more information than does a single gene locus. However, current high-throughput genotyping techniques cannot produce haplotype information. Several statistical methods have recently been proposed to infer haplotypes based on unphased genotypes at several loci. The accuracy, efficiency, and computational time of these...
Topics
- Algorithms
- Bayes Theorem
- Case-Control Studies
- Data Interpretation, Statistical
- Genetics, Population
- Genotype
- Haplotypes
- Humans