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Article

The nucleotide diversity of MICA and MICB suggests the effect of overdominant selection.

Tissue antigens - 1 Dec 2001

Elsner H A, Schroeder M, Blasczyk R

Abstract excerpt

The major histocompatibility complex (MHC) class I-related molecules A and B (MICA and MICB) are stress-inducible cell surface antigens that are recognized by immunocytes bearing the receptor NKG2D. In our study we estimated the average number of synonymous (pis) and nonsynonymous nucleotide substitutions (pia) per site in exons 2-4 of MICA and MICB. In exons 2 and 3 of MICB only nonsynonymous substitutions were...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

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Source

Identifiers

PMID: 11929594
DOI: 10.1034/j.1399-0039.2001.580612.x

Genes

MICA
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The nucleotide diversity of MICA and MICB suggests the effect of overdominant selection.PMID 11929594Read ↗

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High population frequencies of MICA copy number variations originate from independent recombination eventsSemantic proximity Read ↗

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