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Expression and function of the major histocompatibility complex (MHC) class I chain-related A (MICA)*010 in NK cell killing activity.

Human immunology - 1 Sept 2024

Phanabamrung Sonwit, Jumnainsong Amonrat, Anuwongcharoen Nuttapat, Phanus-Umporn Chuleeporn, Rareongjai Sarayot, Leelayuwat Chanvit

Abstract excerpt

The major histocompatibility complex (MHC) class I chain-related A (MICA) plays an important role in stress cell recognition. High polymorphisms of MICA are relevant to NKG2D binding capacity, responses of NK cells and tumor progression. In this study, MICA genotyping of 97 cholangiocarcinoma patients was performed using PCR-SSP. MICA*010 was positively associated with a corrected p-value of < 0.001 (RR=2.16...

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PMID: 39116667
DOI: 10.1016/j.humimm.2024.111085

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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