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Article

Diversity and characterization of polymorphic 5' promoter haplotypes of MICA and MICB genes.

Tissue antigens - 1 Sept 2014

Cox S T, Madrigal J A, Saudemont A

Abstract excerpt

The major histocompatibility complex (MHC) class I-related chain A (MICA) and B (MICB) are ligands for the natural killer group 2, member D (NKG2D) activating receptor expressed on natural killer (NK) cells, natural killer T (NKT) cells, CD8+ T cells and γδ T cells. Natural killer group 2, member D (NKG2D) ligand expression is stress-related and upregulated by infected or oncogenic cells leading to cytolysis....

Read the complete abstract on PubMed

Topics

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Share to Cytotoxicity, Immunologic
Share to Haplotypes
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Ligands

Share to NK Cell Lectin-Like Receptor Subfamily K

Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 24962621
DOI: 10.1111/tan.12400

Genes

MICA
MICB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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