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Article

High frequencies of alleles MICA020 and MICA027 in Amerindians and evidence of positive selection on exon 3.

Genes and immunity - 1 Dec 2008

Oliveira L A, Ribas F, Bicalho M G, Tsuneto L T, Petzl-Erler M L

Abstract excerpt

MICA is a nonclassical polymorphic MHC molecule. We investigated MICA allelic frequencies and MICA-HLA-B-HLA-C haplotypes in Brazilian Amerindians to describe the polymorphism and to extract information about the evolution of MICA gene. Kaingang is the first population described to have a high frequency of MICA*020, found associated with HLA-B*3505-HLA-Cw*0401. Allele MICA*020 probably originated de novo in South...

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Source

Identifiers

PMID: 18784732
DOI: 10.1038/gene.2008.65

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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