Article
MICA polymorphism in a sample of the São Paulo population, Brazil.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2004
Marin M L C, Savioli C R, Yamamoto J H, Kalil Jorge, Goldberg A C
Abstract excerpt
The major histocompatibility complex (MHC) class I chain-related A (MICA) gene, located near HLA-B, codes for protein products with structural similarities to those of classical MHC class I genes, but which neither bind beta(2)-microglobulin nor present peptide. Expressed predominantly on gastrointestinal and tumour epithelial cells, they are stress-induced and interact with C-type lectin like receptor (NKG2D) on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
