Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension.

JAMA - 3 Apr 2002

Psaty Bruce M, Smith Nicholas L, Heckbert Susan R, Vos Hans L, Lemaitre Rozenn N, Reiner Alexander P, Siscovick David S, Bis Joshua, Lumley Thomas, Longstreth W T, Rosendaal Frits R

Abstract excerpt

CONTEXT: A genetic variant in alpha-adducin has been associated with renal sodium reabsorption and salt-sensitive hypertension. Whether this genetic variant modifies the effect of diuretic therapy on the incidence of myocardial infarction (MI) and stroke is unknown. OBJECTIVES: To estimate the in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Calmodulin-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Diuretics

Share to Hypertension

Share to Myocardial Infarction

Share to Stroke

Source

Identifiers

PMID: 11926892
DOI: 10.1001/jama.287.13.1680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11926892-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension.PMID 11926892Read ↗

Diuretic-gene interaction and the risk of myocardial infarction and stroke.Semantic proximity Read ↗

Alpha-adducin polymorphism associated with increased risk of adverse cardiovascular outcomes: results from GENEtic Substudy of the INternational VErapamil SR-trandolapril STudy (INVEST-GENES).Semantic proximity Read ↗

Adducin and hypertension.Semantic proximity Read ↗

Cardiovascular risk in relation to alpha-adducin Gly460Trp polymorphism and systolic pressure: a prospective population study.Semantic proximity Read ↗

Alpha-adducin Gly460Trp variant increases the risk of stroke in hypertensive Dutch women.Semantic proximity Read ↗

Screening for the alpha-adducin Gly460Trp variant in hypertensive patients: a cost-effectiveness analysis.Semantic proximity Read ↗

Association of the alpha-adducin polymorphism with blood pressure and risk of myocardial infarction.Semantic proximity Read ↗

beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke.Semantic proximity Read ↗

Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction.Semantic proximity Read ↗

Role of the adducin family genes in human essential hypertension.Semantic proximity Read ↗

alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension.Semantic proximity Read ↗

alpha-Adducin Gly460Trp polymorphism, left ventricular mass and plasma renin activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.