Article
alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 2000
Clark C J, Davies E, Anderson N H, Farmer R, Friel E C, Fraser R, Connell J M
Abstract excerpt
This study focused on two genes that have previously been implicated in hypertension and may influence renal sodium handling, adducin, and angiotensin I-converting enzyme (ACE). We compared their polymorphic frequencies and interaction in patients with essential hypertension (n=128) and individually age- and gender-matched normotensive control subjects. The alpha-adducin G460W polymorphism was genotyped by DNA...
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