Article
Cardiovascular risk in relation to alpha-adducin Gly460Trp polymorphism and systolic pressure: a prospective population study.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 2005
Li Yan, Thijs Lutgarde, Kuznetsova Tatiana, Zagato Laura, Struijker-Boudier Harry, Bianchi Giuseppe, Staessen Jan A
Abstract excerpt
Preliminary evidence from 1 case-control study suggested that in hypertensive patients, the alpha-adducin 460Trp allele might be associated with a 2-fold higher risk of coronary heart disease. In a prospective population study, we investigated whether the alpha-adducin Gly460Trp polymorphism predicted mortality and morbidity. From August 1985 until July 2003, we randomly recruited 2235 Belgian residents. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.