Article
Screening for the alpha-adducin Gly460Trp variant in hypertensive patients: a cost-effectiveness analysis.
Pharmacogenetics and genomics - 1 Feb 2006
Meckley Lisa M, Veenstra David L
Abstract excerpt
BACKGROUND: Studies have shown that approximately 80% of hypertensive patients do not take diuretics despite their recommendation as a first-line therapy. A recent study reported that hypertensive patients with the Gly460Trp variant in the alpha-adducin gene are more likely to benefit from diuretic therapy. The objective of this study was to evaluate the potential cost effectiveness of screening for the...
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