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Article

tRNA 3' end maturation in archaea has eukaryotic features: the RNase Z from Haloferax volcanii.

Journal of molecular biology - 1 Mar 2002

Schierling Karina, Rösch Sylvia, Rupprecht Renate, Schiffer Steffen, Marchfelder Anita

Abstract excerpt

Here, we report the first characterization and partial purification of an archaeal tRNA 3' processing activity, the RNase Z from Haloferax volcanii. The activity identified here is an endonuclease, which cleaves tRNA precursors 3' to the discriminator. Thus tRNA 3' processing in archaea resembles the eukaryotic 3' processing pathway. The archaeal RNase Z has a KCl optimum at 5mM, which is in contrast to the...

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Identifiers

PMID: 11884130
DOI: 10.1006/jmbi.2001.5395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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