Article
Assigning a function to a conserved archaeal metallo-β-lactamase from Haloferax volcanii.
Extremophiles : life under extreme conditions - 1 Mar 2012
Fischer Susan, John von Freyend Simona, Sabag-Daigle Anice, Daniels Charles J, Allers Thorsten, Marchfelder Anita
Abstract excerpt
The metallo-β-lactamase family of enzymes comprises a large group of proteins with diverse functions in the metabolism of the cell. Among others, this superfamily contains proteins which are involved in DNA and RNA metabolism, acting as nucleases in e.g. repair and maturation. Many proteins have been annotated in prokaryotic genomes as being potential metallo-β-lactamases, but very often the function has not been...
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