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Article

Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity.

The Journal of endocrinology - 1 Mar 2002

Pritchard L E, Turnbull A V, White A

Abstract excerpt

Bioactive peptides derived from the prohormone, pro-opiomelanocortin (POMC), are generated in neurons of the hypothalamus and act as endogenous ligands for the melanocortin-4 receptor (MC4R), a key molecule underlying appetite control and energy homeostasis. It is therefore important to understand many aspects of POMC gene regulation in the brain, as pharmacological manipulation of POMC expression/processing...

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Source

Identifiers

PMID: 11874690
DOI: 10.1677/joe.0.1720411

Genes

POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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