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Article

ACTH: cellular peptide hormone synthesis and secretory pathways.

Results and problems in cell differentiation - 1 Jan 2010

Stevens Adam, White Anne

Abstract excerpt

Adrenocorticotrophic hormone (ACTH) is derived from the prohormone, pro-opiomelanocortin (POMC). This precursor undergoes proteolytic cleavage to yield a number of different peptides which vary depending on the tissue. In the anterior pituitary, POMC is processed to ACTH by the prohormone convertase, PC1 and packaged in secretory granules ready for stimulated secretion. In response to stress, corticotrophin...

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Source

Identifiers

PMID: 19888563
DOI: 10.1007/400_2009_30

Genes

POMC
CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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ACTH: cellular peptide hormone synthesis and secretory pathways.PMID 19888563Read ↗

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