Article
Functional versus structural matching: can the CTLp test be replaced by HLA allele typing?
Human immunology - 1 Mar 2002
Oudshoorn M, Doxiadis I I N, van den Berg-Loonen P M, Voorter C E M, Verduyn W, Claas F H J
Abstract excerpt
Human leukocyte antigen (HLA) incompatibilities are the most important immunological barriers to bone marrow transplant success when using unrelated donors. Until recently, standards for donor selection included serological methods for HLA class I antigens and DNA-based typing for HLA class II alleles. In our center cytotoxic T-lymphocyte precursor (CTLp) assays have been an integrated part of the search...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.