Article
Molecular characterization of HLA-C incompatibilities in HLA-ABDR-matched unrelated bone marrow donor-recipient pairs. Sequence of two new Cw alleles (Cw*02023 and Cw*0707) and recognition by cytotoxic T lymphocytes.
Tissue antigens - 1 Jun 1997
Grundschober C, Rufer N, Sanchez-Mazas A, Madrigal A, Jeannet M, Roosnek E, Tiercy J M
Abstract excerpt
While the influence of HLA-AB and -DRB1 matching on the outcome of bone marrow transplantation (BMT) with unrelated donors is clear, the evaluation of HLA-C has been hampered by its poor serological definition. Because the low resolution of standard HLA-C typing could explain the significant numb...
Topics
- ABO Blood-Group System
- Alleles
- Amino Acid Sequence
- Base Sequence
- Bone Marrow Transplantation
- DNA, Complementary
- Gene Frequency
- HLA-C Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- HLA-DRB3 Chains
- HLA-DRB5 Chains
- Haplotypes
- Histocompatibility Testing
