Article
High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation.
Blood - 15 May 1996
Speiser D E, Tiercy J M, Rufer N, Grundschober C, Gratwohl A, Chapuis B, Helg C, Löliger C C, Siren M K, Roosnek E, Jeannet M
Abstract excerpt
As compared with related HLA-identical sibling donors, bone marrow transplantation (BMT) with phenotypically HLA ABDR-compatible unrelated donors is associated with increased mortality. This may be due to hidden HLA incompatibilities not detected by conventional typing. We have analyzed 44 unrelated patient-donor pairs who were matched for HLA-A, -B, and -DR by routine tissue typing. Our comprehensive HLA typing...
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