Article
High resolution HLA matching associated with decreased mortality after unrelated bone marrow transplantation.
Blood - 15 May 1996
Speiser D E, Tiercy J M, Rufer N, Grundschober C, Gratwohl A, Chapuis B, Helg C, Löliger C C, Siren M K, Roosnek E, Jeannet M
Abstract excerpt
As compared with related HLA-identical sibling donors, bone marrow transplantation (BMT) with phenotypically HLA ABDR-compatible unrelated donors is associated with increased mortality. This may be due to hidden HLA incompatibilities not detected by conventional typing. We have analyzed 44 unrela...
Topics
- Alleles
- Bone Marrow Transplantation
- Cause of Death
- Female
- Follow-Up Studies
- Graft vs Host Disease
- HLA Antigens
- Histocompatibility Testing
- Humans
- Infections
- Life Tables
- Male
- Survival Analysis
- Survival Rate
- Transplantation, Homologous
