Article
Are We Ready for Epitope-Based HLA Matching in Clinical Organ Transplantation?
Transplantation - 1 Aug 2017
Duquesnoy Rene J
Abstract excerpt
This overview describes recent developments demonstrating the significance of epitopes in HLA antibody responses and matching for organ transplantation. HLA epitopes are defined by molecular modeling and amino acid comparisons between HLA alleles and the HLAMatchmaker algorithm considers eplets as essential components. Each allele represents a distinct string of eplets and matching is done by aligning donor and...
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