Article
Cytotoxic T lymphocyte precursor frequency analysis in the selection of HLA matched unrelated donors for hematopoietic stem cell transplantation: the correlation of CTLp frequency with HLA class I genotyping and aGVHD development.
Neoplasma - 1 Jan 2002
Dolezalová L, Vraná M, Dobrovolná M, Loudová M, Cukrová V, Vítek A, Sajdová J, Starý J, Sedlácek P
Abstract excerpt
The selection of human leukocyte antigen (HLA) compatible unrelated donors for hematopoietic stem cell transplantation (HSCT) is based on the direct genotyping of HLA class I and class II alleles (HLA-A, -B, -C, -DRB1, -DQB1 loci). The cellular test estimating the frequency of cytotoxic T lymphocyte precursors (CTLp) has been included into the selection procedure of unrelated donors to detect the class I...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.