Article
Selection of unrelated bone marrow donors by serology, molecular typing and cellular assays.
Transplant immunology - 1 Aug 2002
Tiercy Jean-Marie, Villard Jean, Roosnek Eddy
Abstract excerpt
As compared to hematopoietic stem cell transplantation (HSCT) with HLA genotypically identical donors, phenotypically matched unrelated HSCT is associated with lower survival. Serologically undisclosed HLA disparities account for the increased rate of post-transplant complications. With more than 1300 alleles currently identified, high-resolution molecular typing techniques have to be applied to distinguish the...
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