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Indirectly Recognized HLA-C Mismatches and Their Potential Role in Transplant Outcome

12 May 2014

Abstract excerpt

HLA-C mismatches are clearly associated to alloreactivity after hematopoietic stem-cell transplantation; in a number of large cohorts, HLA-C mismatches are correlated to an increased risk of acute graft-versus-host disease (GVHD) or even impaired survival. While for HLA-A and -B, both antigenic as well as allelic mismatches are associated with an increased risk of acute GVHD, such an increased risk is only...

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PMID: 24860572
DOI: 10.3389/fimmu.2014.00210

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